heteroduplex dna การใช้

One such example is the heteroduplex DNA strand formed in hybridization processes, usually for biochemistry-based phylogenetical analyses.
Holliday's original model assumed that heteroduplex DNA would be present on both chromosomes, but experimental data on yeast refuted this.
When mismatches occur in heteroduplex DNA, the sequence of one strand will be repaired to bind the other strand with perfect complementarity, leading to the conversion of one sequence to another.
At various steps of the recombination process, heteroduplex DNA ( double-stranded DNA consisting of single strands from each of the two homologous chromosomes which may or may not be perfectly complementary ) is formed.
Therefore, it should be noted that while SDSA produces non-crossover products because flanking markers of heteroduplex DNA are not exchanged, gene conversion does occur, wherein nonreciprocal genetic transfer takes place between two homologous sequences.